Human CXCL8 is a 77 amino acid protein that is the prototypical CXC chemokine which is expressed by fibroblasts and keratinocytes. Also known as Interleukin 8, this chemokine binds and activates two G protein-coupled receptors, CXCR1/CXCR2 on a variety of cells such as neutrophils, T-cells, endothelial cells, macrophages and keratinocytes. CXCL8 is N-terminally processed to yield the major in vivo species, the 6-77 variant.
| Purity|| Assessed by HPLC, Mass Spectrometry, and NMR |
| Source|| Human protein expressed in E. coli|
| Physical form|| Lyophilized powder|
| Solubility|| Freely Soluble in Water|
| Accession #|| |
| Endotoxin level|| <0.01 EU per 1µg of the protein by LAL method|