Description: Human CXCL5 is a 78 amino acid protein expressed by TNF- activated eosinophils and recruits CXCR2+ neutrophils to inflamed tissues. CXCL5 has been implicated as peripheral mediator of UVB-induced pain. Secreted full-length CXCL5 can be N-terminally truncated by leukocyte proteases to produce a 5-78 variant that is an 8-fold more potent chemoattractant than the full-length version.
Amino Acid Sequence:
AGPAAAVLRE LRCVCLQTTQ GVHPKMISNL QVFAIGPQCS KVEVVASLKN GKEICLDPEA PFLKKVIQKI LDGGNKEN
Molecular Weight:
8352.8 Daltons
Fusion Tag:
N/A
Special Characteristic(s):
Purity:
Purity assessed by HPLC, Mass Spectrometry, and NMR*
Source:
Human protein expressed in E. coli
Physical Form:
Lyophilized
Solubility:
Freely soluble in water **
Storage Conditions:
Product Form
Temperature
Storage Time
-20C to -80C
12 months
4C
6 months
RT
1 month
Additional comments or descriptive information:
* All recombinant proteins produced and sold by Protein Foundry, LLC are endotoxin-free <0.01 EU/ug of protein and validated using RP-HPLC, 2D-NMR, and functional reporter assay where available.
** Avoid repeated freeze-thaw cycles after reconstitution
