Description: Human CXCL11, also known as Interferon Inducible T-Cell a, I-TAC, SCYB9B, H174 and beta -R1, is a ligand for the G protein coupled receptors CXCR3 and CXCR7 whose production is induced by interferon production. It is expressed in many cell types including peripheral blood leukocytes, pancreas and liver astrocytes. CXCL11 induces calcium release in activated T-cells and is chemotactic for interleukin-stimulated T-cells.
Amino Acid Sequence:
FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF
Purity assessed by HPLC, Mass Spectrometry, and NMR*
Human protein expressed in E. coli
Freely soluble in water **
-20C to -80C
Additional comments or descriptive information:
* All recombinant proteins produced and sold by Protein Foundry, LLC are endotoxin-free <0.01 EU/ug of protein and validated using RP-HPLC, 2D-NMR, and functional reporter assay where available.
** Avoid repeated freeze-thaw cycles after reconstitution