Description: Human CX3CL1 is a membrane protein consisting of a mucin-like stalk attached to a transmembrane domain containing a C-terminal tail. CX3CL1 is the ligand to the G protein-coupled receptor CX3CR1. CX3CL1 and its receptor have been shown to be a involved in the cellular processes leading to atherosclerosis, where a deletion of the gene specific to the CX3CR1 receptor in transgenic mouse models lead to a decrease in the disease.
Amino Acid Sequence:
Purity assessed by HPLC, Mass Spectrometry, and NMR*
Human protein expressed in E. coli
Freely soluble in water **
-20C to -80C
Additional comments or descriptive information:
* All recombinant proteins produced and sold by Protein Foundry, LLC are endotoxin-free <0.01 EU/ug of protein and validated using RP-HPLC, 2D-NMR, and functional reporter assay where available.
** Avoid repeated freeze-thaw cycles after reconstitution