Description: Human CCL23, also designated CK-beta-8, Macrophage inflammatory protein 3 (MIP-3), Myeloid progenitor inhibitory factor 1 (MPIF-1) and small-inducible cytokine A23, attracts monocytes, resting T-lymphocytes, and neutrophils through activation of the G protein-coupled receptor CCR1. Alternative splicing results in a second isoform 116 amino acids in length. Additional proteolytic processing at the N terminus (e.g. CCL23 25-99) reportedly yields a more potent form of the chemokine.
Amino Acid Sequence:
Purity assessed by HPLC, Mass Spectrometry, and NMR*
Human protein expressed in E. coli
Freely soluble in water **
-20C to -80C
Additional comments or descriptive information:
* All recombinant proteins produced and sold by Protein Foundry, LLC are endotoxin-free <0.01 EU/ug of protein and validated using RP-HPLC, 2D-NMR, and functional reporter assay where available.
** Avoid repeated freeze-thaw cycles after reconstitution