CCL22(3-69), Human

Your Price: $250.00

Product: PFP023

AA seq: YGANMEDSVC CRDYVRYRLP LRVVKHFYWT SDSCPRPGVV LLTFRDKEIC ADPRVPWVKM ILNKLSQ

MW (Da): 7,932.30

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Isotope labeling

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Description
Literature
Technical Specifications

Human CCL22(3-69) (C-C motif ligand 22(3-69); also known as MDC(3-69)) is a 67-amino-acid N-terminally truncated CC chemokine generated by CD26/dipeptidyl peptidase IV (DPIV) cleavage. It retains CCR4 agonist activity with slightly reduced potency but enhanced resistance to further degradation. It also binds ACKR2. This form is detected in inflammatory fluids and may sustain Th2 responses. These interactions highlight CCL22(3-69)'s role in chronic allergic inflammation.

Amino Acid Sequence	YGANMEDSVC CRDYVRYRLP LRVVKHFYWT SDSCPRPGVV LLTFRDKEIC ADPRVPWVKM ILNKLSQ
Molecular Weight	7,932.3
Source	E. coli-derived human CCL22 protein Tyr27-Gln93
UniProt ID	O00626

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Purity	Purity assessed by HPLC, Mass Spectrometry, and NMR
Source	Human protein expressed in E. coli
Physical Form	Lyophilized
Solubility	Freely soluble in water
Solution Stability	1 months at 4 °C 12 months at -20 to -80 °C