Description: CCL22 protein is expressed in E. coli, processed, refolded and purified to yield the native, secreted form of the mature chemokine. CCL22, previously known as MDC, is most closely related to CCL17 and is expressed predominantly in the thymus. CCL22 is chemotactic for Th2 T cells and macrophages and signals through CCR4.
Amino Acid Sequence:
GPYGANMEDSVCCRDYVRYRLPLRVVKHFYWTSDSCPRPGVVLLTFRDK
EICADPRVPWVKMILNKLSQ
Molecular Weight:
8086.47 Daltons
Fusion Tag:
N/A
Special Characteristic(s):
Purity:
Purity assessed by HPLC, Mass Spectrometry, and NMR*
Source:
Human protein expressed in E. coli
Physical Form:
Lyophilized
Solubility:
Freely soluble in water **
Storage Conditions:
Product Form
Temperature
Storage Time
-20C to -80C
12 months
4C
6 months
RT
1 month
Additional comments or descriptive information:
* All recombinant proteins produced and sold by Protein Foundry, LLC are endotoxin-free <0.01 EU/ug of protein and validated using RP-HPLC, 2D-NMR, and functional reporter assay where available.
** Avoid repeated freeze-thaw cycles after reconstitution