CCL21, Human

Your Price: $250.00

Product: PFP010

AA seq: SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCK RTERSQTPKG P

MW (Da) 12247.2

Units

Isotope labeling

Quantity

Product Details
Validation
Literature
Database Links

Description: CCL21 is a human chemokine that recruits normal immune cells and metastasizing tumor cells to lymph nodes through activation of the G protein-coupled receptor CCR7. Originally called SLC or exodus-2, CCL21 is expressed in high endothelial venules of lymph nodes, spleen, and Peyer's patches as well as lymphatic endothelium in peripheral tissues. CCL21 directs the migration of CCR7-expressing lymphocytes and antigen-activated dendritic cells. CCL21 contains 6 conserved cysteines, in contrast to the 4 that are more typical of CC chemokines. CCL21 induces chemotactic migration of thymocytes and activated T-cells, but not B-cells, macrophages, or neutrophils.

Amino Acid Sequence	SDGGAQDCCLKYSQRKIPAKVVRSYRKQEPSLGCSIPAILFLPRKRSQAELCAD PKELWVQQLMQHLDKTPSPQKPAQGCRKDRGASKTGKKGKGSKGCKRTERSQTPKGP
Molecular Weight:	12247.2 Daltons
Fusion Tag:	N/A
Special Characteristic(s):	N/A
Purity:	Purity assessed by HPLC, Mass Spectrometry, and NMR^*
Source:	Human protein expressed in E. coli
Physical Form:	Lyophilized
Solubility:	Freely soluble in water **
Storage Conditions:

Product Form	Temperature	Storage Time
Lyophilized	-20C to -80C	12 months
Lyophilized	4C	6 months
Lyophilized	RT	1 month

Additional comments or descriptive information:

* All recombinant proteins produced and sold by Protein Foundry, LLC are endotoxin-free <0.01 EU/ug of protein and validated using RP-HPLC, 2D-NMR, and functional reporter assay where available.

** Avoid repeated freeze-thaw cycles after reconstitution

Item In Cart

CCL17, Human

$250.00

Select Options

Item In Cart

CCL2 with C-terminal tag, Human

$500.00

Select Options

Item In Cart

CCL24 with C-terminal tag, Human

$500.00

Item In Cart

$250.00

Item In Cart

$250.00

CCL21, Human

Choose Options

Related Items