Description: CCL19 protein is expressed in E. coli, processed, refolded and purified to yield the native, secreted form of the mature chemokine. Originally termed MIP-3beta or ELC, CCL19 is expressed in thymus and lymph nodes. The cognate receptor for CCL19 is CCR7 and directs the trafficking of B and T cells.
Amino Acid Sequence:
GTNDAEDCCLSVTQKPIPGYIVRNFHYLLIKDGCRVPAVVFTTLRGRQLCAPPDQPW
VERIIQRLQRTSAKMKRRSS
Molecular Weight:
8796.26 Daltons
Fusion Tag:
N/A
Special Characteristic(s):
Purity:
Purity assessed by HPLC, Mass Spectrometry, and NMR*
Source:
Human protein expressed in E. coli
Physical Form:
Lyophilized
Solubility:
Freely soluble in water **
Storage Conditions:
Product Form
Temperature
Storage Time
-20C to -80C
12 months
4C
6 months
RT
1 month
Additional comments or descriptive information:
* All recombinant proteins produced and sold by Protein Foundry, LLC are endotoxin-free <0.01 EU/ug of protein and validated using RP-HPLC, 2D-NMR, and functional reporter assay where available.
** Avoid repeated freeze-thaw cycles after reconstitution
