Description: CCL18, previously identified as DC-CK1 or PARC, is expressed by dendritic cells and is chemotactic for naïve T cells. The 7 transmembrane GPCR CCR8 and the 6 transmembrane protein, membrane-associated phosphatidylinositol transfer protein 3, PITPNM3, are receptors for CCL18. The ligand was shown to have antagonist properties against CCR3.
Amino Acid Sequence:
Purity assessed by HPLC, Mass Spectrometry, and NMR*
Human protein expressed in E. coli
Freely soluble in water **
-20C to -80C
Additional comments or descriptive information:
* All recombinant proteins produced and sold by Protein Foundry, LLC are endotoxin-free <0.01 EU/ug of protein and validated using RP-HPLC, 2D-NMR, and functional reporter assay where available.
** Avoid repeated freeze-thaw cycles after reconstitution