Description: Recombinant human beta defensin 2 or HBD2 exhibits antimicrobial activity against gram-negative bacteria and gram-positive bacteria. This cytokine may act as a ligand for C-C chemokine receptor CCR6. It binds to both human and mouse CCR6 and induces chemotactic activity of CCR6-expressing cells.
Amino Acid Sequence:
GIGDPVTCLK SGAICHPVFC PRRYKQIGTC GLPGTKCCKK P
Molecular Weight:
4328.2 Daltons
Fusion Tag:
N/A
Special Characteristic(s):
Purity:
Purity assessed by HPLC, Mass Spectrometry, and NMR*
Source:
Human protein expressed in E. coli
Physical Form:
Lyophilized
Solubility:
Freely soluble in water **
Storage Conditions:
Product Form
Temperature
Storage Time
-20C to -80C
12 months
4C
6 monts
RT
1 month
Additional comments or descriptive information:
* All recombinant proteins produced and sold by Protein Foundry, LLC are endotoxin-free <0.01 EU/ug of protein and validated using RP-HPLC, 2D-NMR, and functional reporter assay where available.
** Avoid repeated freeze-thaw cycles after reconstitution
