Description: Recombinant human beta defensin 2 or HBD2 exhibits antimicrobial activity against gram-negative bacteria and gram-positive bacteria. This cytokine may act as a ligand for C-C chemokine receptor CCR6. It binds to both human and mouse CCR6 and induces chemotactic activity of CCR6-expressing cells.
Amino Acid Sequence:
GIGDPVTCLK SGAICHPVFC PRRYKQIGTC GLPGTKCCKK P
Purity assessed by HPLC, Mass Spectrometry, and NMR*
Human protein expressed in E. coli
Freely soluble in water **
-20C to -80C
Additional comments or descriptive information:
* All recombinant proteins produced and sold by Protein Foundry, LLC are endotoxin-free <0.01 EU/ug of protein and validated using RP-HPLC, 2D-NMR, and functional reporter assay where available.
** Avoid repeated freeze-thaw cycles after reconstitution