Cooperative chemokine signaling influencing T cell movement from blood to tissue

Chemokine positioning assists extravasation of pathogenic human T cells
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CXCL12 potentiates chromatin compaction via ACKR3 activation

CXCL12 and its receptor CXCR4 have well known roles in bone marrow homing and  mobilization of hematopoietic stem cells and neutrophils, but inflammatory neutrophil  recruitment is governed by CXCR2 and its
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Origins of metamorphism in XCL1

A new TiBS Spotlight features the work of Protein Foundry scientists and collaborators on the evolution of a highly unusual chemokine.
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