Human CXCL3 (5-73) (MIP2-beta; GRO-gamma) is a 68 amino acid ELR+ chemokine that guides neutrophils to sites of inflammation or infection by binding to the CXCR2 receptor. Produced by cells like macrophages in response to injury or pathogens, it plays a key role in amplifying immune responses and is implicated in conditions like rheumatoid arthritis and cancer, where it can either aid immunity or promote pathology depending on context.
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