CXCL16, Human

Your Price: $250.00

Product: PFP053

AA seq: NEGSVTGSCY CGKRISSDSP PSVQFMNRLR KHLRAYHRCL YYTRFQLLSW SVCGGNKDPW VQELMSCLDL KECGHAYSGI VAHQKHLLP

MW (Da) 10156.7

Units

Isotope labeling

Quantity

Product Details
Validation
Literature
Database Links

Description: Recombinant human CXCL16 protein is expressed in E. coli, refolded and purified to yield the 89 residue chemokine domain of the polypeptide. Human CXCL16 is produced in the lymphoid organs by dendritic cells found in the T cell zones, and the red pulp of the spleen. CXCL16 lacks the ELR motif common in most CXC chemokines and is the second, along with fractalkine (CXC3C1) to contain a transmembrane domain. CXCL16 is a ligand to the receptor CXCR6 (also known as Bonzo, STRL33 or TYMSTR), a receptor previously shown to be a co-receptor for HIV entry. CXCR6 and CXCL16 have been linked to many diseases in mice and humans including autoimmunity, inflammatory disorders, graft-versus-host disease, cancer and HIV-AIDS

Amino Acid Sequence:

NEGSVTGSCY CGKRISSDSP PSVQFMNRLR KHLRAYHRCL YYTRFQLLSW
SVCGGNKDPW VQELMSCLDL KECGHAYSGI VAHQKHLLP

Molecular Weight:

10156.7 Daltons

Fusion Tag:

N/A

Special Characteristic(s):

N/A

Purity:

Purity assessed by HPLC, Mass Spectrometry, and NMR^*

Source:

Human protein expressed in E. coli

Physical Form:

Lyophilized

Solubility:

Freely soluble in water **

Storage Conditions:

Product Form	Temperature	Storage Time
Lyophilized	-20C to -80C	12 months
Lyophilized	4C	6 months
Lyophilized	RT	1 month

Additional comments or descriptive information:

* All recombinant proteins produced and sold by Protein Foundry, LLC are endotoxin-free <0.01 EU/ug of protein and validated using RP-HPLC, 2D-NMR, and functional reporter assay where available.

** Avoid repeated freeze-thaw cycles after reconstitution

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