Description: Recombinant human CCL15 is expressed in E. coli, refolded and purified to yield the full-length secreted protein. CCL15, initially called MIP1-delta or MIP-5, activates cells via CCR1 and CCR3 and is expressed in T and B lymphocytes, NK cells, monocytes, and monocyte-derived dendritic cells. CCL15 is chemotactic for T cells and monocytes.
Amino Acid Sequence:
QFINDAETEL MMSKLPLENP VVLNSFHFAA DCCTSYISQS IPCSLMKSYF ETSSECSKPG VIFLTKKGRQ VCAKPSGPGV QDCMKKLKPY SI
Purity assessed by HPLC, Mass Spectrometry, and NMR*
Human protein expressed in E. coli
Freely soluble in water **
-20C to -80C
Additional comments or descriptive information:
* All recombinant proteins produced and sold by Protein Foundry, LLC are endotoxin-free <0.01 EU/ug of protein and validated using RP-HPLC, 2D-NMR, and functional reporter assay where available.
** Avoid repeated freeze-thaw cycles after reconstitution